The Merc with a Mouth has had a number of insane adventures since his debut in 1991, but it looks like Marvel will be bringing those to an end with Deadpool #250. Marvel has announced that Wade Wilson will meet his end in the issue, which is also #45 of his current solo series and will mark the end of the run.

In the official solicitation text for the issue, Marvel says: “That’s right – if you add together all the Deadpool series (creatively) issue 45 is the big 250th issue of Deadpool! What better way to celebrate than to end the series? In our over-sized main story, Ultimatum comes at Deadpool for revenge, so he has no choice but to take them on – ALL OF THEM. Then, in an Infinity Gauntlet crossover, what would Deadpoll do if he got the six gems from Thanos? Plus, a slew of stories showcasing Deadpool’s closest friends and allies by special guest writers! Also, SPOILER: Deadpool dies at the end of the issue.”

Deadpool #250 will hit shelves in April.